发明名称 Forma cristallina di un inibitore di interazione tra mdm2/4 e p53
摘要 <p>A crystalline form of (S)-1-(4-Chloro-phenyl)-7-isopropoxy-6-methoxy-2-(4-{methyl-[4-(4-methyl-3-oxo-piperazin-1-yl)-trans-cyclohexylmethyl]-amino}-phenyl)-1,4-dihydro-2H-isoquinolin-3-one, which is useful in the treatment of a disease or disorder associated with the interaction between p53, or variants thereof, and MDM2 and/or MDM4, or variants thereof, respectively.</p>
申请公布号 SMT201500059(B) 申请公布日期 2015.05.05
申请号 SM20150000059T 申请日期 2015.03.10
申请人 NOVARTIS AG 发明人 BERHAUSEN JOERG;REN HAIXIA
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