Deuterium-enriched aldehydes

摘要

The present invention generally relates to deuterium-enriched aldehydes, compositions comprising deuterium-enriched aldehydes, and methods for slowing the rate of aldehyde autoxidation. In one aspect, the present invention provides a composition comprising a compound of structure 1:;
wherein: there are at least 6×1018 molecules of the aldehyde and Rx is hydrogen, wherein the deuterium isotope in Rx is in an amount greater than 0.10 percent of the hydrogen atoms present in Rx.

主权项

1. A method of modulating the behavior of insects, comprising: introducing a modulating composition to an area to be protected from the insects, the modulating composition, comprising: a deuterium-enriched aldehyde pheromone of structure 1: wherein: there are at least 6×1018 molecules of the aldehyde in the composition; Rx is hydrogen, wherein the deuterium isotope is present in an amount greater than 0.10% of the Rx hydrogen atoms; R1, R2 and R3 are independently selected from hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, heteroalkyl, substituted heteroalkyl, aryl, substituted aryl, heteroaryl, and substituted heteroaryl; alternatively the CR1R2R3 moiety forms a group selected from: an aryl, substituted aryl, heteroaryl, and substituted heteroaryl; alternatively, CR1R2 moiety forms a group selected from: an alkenyl and substituted alkenyl; alternatively, CR1R2R3 moiety forms a group selected from: an alkynyl and substituted alkynyl; and, optionally, the aldehyde is substituted with C(O)Ry, wherein Ry is hydrogen, wherein the deuterium isotope is optionally present in an amount greater than 0.10% of the Ry hydrogen atoms, provided that Rx is optionally H when the deuterium isotope is present in an amount greater than 0.10% of the Ry hydrogen atoms.