发明名称 |
REDUCTION-TRIGGERED ANTIBACTERIAL SIDEROMYCINS |
摘要 |
A compound is provided, comprising: an Fe(III)-binding or an Fe(III)-bound siderophore; one or more optional linker covalently bound to the siderophore; a drug; and an Fe(III) to Fe(II) reduction triggered linker bound to the drug and the linker or, if no linker is present, then bound to the drug and the siderophore. Compositions and methods including the compound are also provided. |
申请公布号 |
WO2015061630(A2) |
申请公布日期 |
2015.04.30 |
申请号 |
WO2014US62069 |
申请日期 |
2014.10.23 |
申请人 |
MILLER, MARVIN J.;JI, CHENG |
发明人 |
MILLER, MARVIN J.;JI, CHENG |
分类号 |
A61K31/165;C07C239/18 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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