发明名称 SULFORAPHANE ISOLATION AND PURIFICATION
摘要 The present invention relates to methods of isolating and purifying sulforaphane. More specifically, the present invention relates to methods of isolating and purifying sulforaphane from natural sources. The present invention also relates to methods of forming high purity complexes of sulforaphane with cyclodextrin.
申请公布号 US2015119359(A1) 申请公布日期 2015.04.30
申请号 US201314404781 申请日期 2013.05.31
申请人 PharmAgra Labs, Inc. 发明人 Damireddi Sahadeva Reddy;Akue Kpakpo Ambroise;Nelson Jared K.;Frisbee Albert Roger;Newsome Peter Wyatt
分类号 A61K31/275;A61K47/48;C08L5/16 主分类号 A61K31/275
代理机构 代理人
主权项 1. A method of isolating sulforaphane and/or a sulforaphane analog from a natural source thereof, the method comprising: a) mixing the natural source of sulforaphane and/or sulforaphane analog with cyclodextrin in a suitable solvent and with or without heat; b) cooling the mixture to a temperature within the range of −10° C. to +25° C. to promote the formation of a precipitate of a complex between the sulforaphane or suloforaphane analog and the cyclodextrin; and c) collecting the precipitate formed.
地址 Brevard NC US