发明名称 PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE THEREOF
摘要 <p>An optically active 4-phenylthiazole derivative having a thrombopoietin receptor agonist activity and a pharmaceutical composition containing the present compound as an active ingredient are created, and a platelet production regulating agent which can be orally administered is provided. Disclosed is a pharmaceutical composition containing, as an active ingredient, an optically active compound represented by the formula: wherein, R 1 is a halogen atom or C1-C3 alkyloxy; R 2 is C1-C8 alkyl R 3 is C1-C8 alkyl R 4 and R 5 are each independently a fluorine atom or chlorine atom; R 6 is C1-C3 alkyl or C1-C3 alkyloxy * indicates that a carbon atom marked with an asterisk is an asymmetric carbon, a pharmaceutically acceptable salt thereof, or a solvate thereof.</p>
申请公布号 SI2184279(T1) 申请公布日期 2015.04.30
申请号 SI20080031361T 申请日期 2008.07.29
申请人 SHIONOGI & CO., LTD. 发明人 TAKAYAMA MASAMI;KUROSE NORIYUKI
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