发明名称 所与の標的に対してアフィニティーを有するhNGALおよび類縁タンパク質のムテイン
摘要 <p>The present invention relates to novel muteins derived from human lipocalin 2 (hNGAL) and related proteins that bind a given non-natural ligand with detectable affinity. The invention also relates to corresponding nucleic acid molecules encoding such a mutein and to a method for their generation. The invention further relates a method for producing such a mutein. Furthermore, the invention is directed to a pharmaceutical composition comprising such a lipocalin mutein as well as to various uses of the mutein.</p>
申请公布号 JP5711118(B2) 申请公布日期 2015.04.30
申请号 JP20110514065 申请日期 2009.06.24
申请人 发明人
分类号 C12N15/09;A61K38/00;A61K47/42;A61K47/48;A61K51/00;A61P35/00;C07K14/47;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;G01N33/53 主分类号 C12N15/09
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