发明名称 |
INTEGRATED ORGAN AND TISSUE PRINTING METHODS, SYSTEM AND APPARATUS |
摘要 |
A method of making an organ or tissue comprises: (a) providing a first dispenser containing a structural support polymer and a second dispenser containing a live cell-containing composition; (b) depositing a layer on said support from said first and second dispenser, said layer comprising a structural support polymer and said cell-containing composition; and then (c) iteratively repeating said depositing step a plurality of times to form a plurality of layers one on another, with separate and discrete regions in each of said layers comprising one or the other of said support polymer or said cell-containing composition, to thereby produce provide a composite three dimensional structure containing both structural support regions and cell-containing regions. Apparatus for carrying out the method and composite products produced by the method are also described. |
申请公布号 |
US2015119994(A1) |
申请公布日期 |
2015.04.30 |
申请号 |
US201414476359 |
申请日期 |
2014.09.03 |
申请人 |
Wake Forest University Health Sciences |
发明人 |
Kang Hyun-Wook;Lee Sang Jin;Atala Anthony;Yoo James J. |
分类号 |
B29C67/00;A61L27/52;A61L27/26;A61L27/38 |
主分类号 |
B29C67/00 |
代理机构 |
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代理人 |
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主权项 |
1. A method of printing an organ or tissue in a plurality of layers, comprising:
(a) providing a first dispenser containing a structural support polymer and a second dispenser containing a live cell-containing composition; (b) depositing a layer on said support from said first and second dispenser, said layer comprising a structural support polymer and said cell-containing composition; and then (c) iteratively repeating said depositing step a plurality of times to form a plurality of layers one on another, with separate and discrete regions in each of said layers separately deposited by one or the other of said syringes, to thereby produce a composite three dimensional structure containing both structural support regions and cell-containing regions. |
地址 |
Winston-Salem NC US |