Thiazole Compounds and Uses Thereof

摘要

The present invention relates to a compound of Formula (I), or an isomer, pharmaceutically acceptable salt and solvate thereof; the present invention further relates to a pharmaceutical composition, which comprises the compound of Formula (I), or isomer, pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents; the present invention further relates to the use of the compound of Formula (I), or isomer, pharmaceutically acceptable salt or solvate thereof, for anti-apoptosis, prophylaxis or treatment of a disease or symptom associated with apoptosis, especially for protecting myocardial cells, and prophylaxis or treatment of a disease or symptom associated with cardiomyocyte apoptosis.;

主权项

1. A compound of Formula (I), or an isomer, pharmaceutically acceptable salt and solvate thereof, wherein R1 represents hydrogen, alkyl, substituted alkyl, cycloalkyl, cycloalkyl-alkyl, phenyl, substituted phenyl, phenylalkyl, substituted phenylalkyl; R2 represents phenyl, substituted phenyl.