| 发明名称 |
BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE |
| 摘要 |
Disclosed are methods for stimulating or increasing β-cell replication or growth, e.g., for increasing insulin secretion, and methods of treating disorders such as diabetes, as well as related compositions and formulations. |
| 申请公布号 |
US2015119399(A1) |
申请公布日期 |
2015.04.30 |
| 申请号 |
US201314371699 |
申请日期 |
2013.01.10 |
| 申请人 |
President and Fellows of Harvard College ;The Brigham and Women's Hospital, Inc. |
发明人 |
Melton Douglas A.;Annes Justin P.;Rubin Lee L. |
| 分类号 |
A61K31/4985;A61K45/06;A61K31/519 |
主分类号 |
A61K31/4985 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of increasing β-cell replication in a population of pancreatic cells, the method comprising: contacting a population of pancreatic cells with an inhibitor of a phosphodiesterase. |
| 地址 |
Cambridge MA US |
