发明名称 |
A CRYSTALLINE ANHYDROUS FORM OF CABAZITAXEL, PROCESS FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF |
摘要 |
The present invention relates to a new anhydrous crystalline form of Cabazitaxel of formula (I), designated as form H. A further object of the present invention is a processes for the preparation of the above mentioned form H by recrystallization of Cabazitaxel from a mixture of decanoyl- and octanoyl triglycerides or from glycerol trioctanoate. Form H of Cabazitaxel is useful for the preparation of Cabazitaxel, Cabazitaxel salts, and polymorphic forms thereof. It is also particularly useful as a medicament, especially for the treatment of cancers. |
申请公布号 |
CA2928305(A1) |
申请公布日期 |
2015.04.30 |
申请号 |
CA20142928305 |
申请日期 |
2014.10.09 |
申请人 |
INDENA S.P.A. |
发明人 |
CABRI, WALTER;CICERI, DANIELE;DOMENIGHINI, LUCA;GAMBINI, ANDREA;PETERLONGO, FEDERICO |
分类号 |
C07D305/14;A61K31/337;A61P35/00 |
主分类号 |
C07D305/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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