发明名称 5-Amino-4-hydroxypentoyl amides
摘要 <p>HIV inhibitors of formula (I) wherein R1 is halo, C1-4 alkoxy, trifluoromethoxy; R2 is a group of formula (A); R3 is a group of formula (B); R4 is a group of formula (C); n is 0 or 1; A is CH or N; R5 and R6 are hydrogen, C1-4 alkyl, halo; R7 and R8 are C1-4 allyl or C1-4 alkoxy-C1-4 alkyl; R9 is C1-4 allyl, cyclopropyl, trifluoromethyl, C1-4 alkoxy, or dimethylamino; R10 is hydrogen, C1-4 alkyl, cyclopropyl, trifluoromethyl, C1-4 alkoxy, or dimethylamino; pharmaceutically acceptable addition salts and solvates thereof; pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds.</p>
申请公布号 AP3217(A) 申请公布日期 2015.04.30
申请号 AP20120006228 申请日期 2010.12.10
申请人 MEDIVIR AB;JANSSEN R & D 发明人 KESTELEYN BART RUDOLF ROMANIE;SCHEPENS WIM BERT GRIET;WEGNER JÖRG KURT
分类号 C07D213/64;A61K31/506;A61P31/18;C07D213/74;C07D277/30;C07D401/12;C07D405/12;C07D417/12;C07D493/04 主分类号 C07D213/64
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