SUBSTITUTED XANTHINE DERIVATIVES

摘要

This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention relates to novel substituted xanthine derivatives that are derivatives of pentifylline. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions for which pentifylline and related compounds are beneficial.

主权项

1. A compound of Formula A: or pharmaceutically acceptable salts thereof, wherein each of X1a, X1b, X2a, X2b, X3a, X3b, X4a, X4b, X5a, X5b and X6 is independently hydrogen or deuterium; and each of R1, R2, and R3, is independently CH3 or CD3; with the proviso that if each X is hydrogen, then at least one R is CD3.