Improved methods and compositions for safe and effective treatment of erythema

摘要

Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier. 6361193_1 (GHMaers) P91331.AU.1 ONIAM Figure I. DaY 15 Dav 29 $3040 0- 3 6 9 Q 3 6 12 3 ie1 Time Poini (hour) -- 2-- 09iQD - 0 I nBID ----- 0.18%QD k elde- - l