MOTION ACTIVATED SEPTUM PUNCTURING DRUG DELIVERY DEVICE

摘要

A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

主权项

1. A wearable drug delivery apparatus for administering a drug to a subject, the drug delivery system comprising:
a housing having a base surface configured to be positioned proximate the subject's skin, the base surface defining a base plane; an actuator positioned within the housing; a reservoir positioned within the housing and a longitudinal axis, a proximal end and a distal end, the longitudinal axis being substantially parallel to the base plane; a plunger movably mounted in the reservoir, the plunger being movable along the longitudinal axis; a needle fluidly connected to the reservoir by a flexible canal, the needle configured for positioning in flesh of the subject with a tip of the needle positioned beneath a surface of the flesh; at least one gear operatively connected to the actuator and the plunger such that rotational motion of the at least one gear driven by the actuator results in translational motion of the plunger along the longitudinal axis of the reservoir; a controller positioned within the housing, the controller configured to drive the actuator by a pulse width modulation to rotate the gears and cause the plunger to translate within the reservoir, the plunger and reservoir configured to cause the drug to flow from the reservoir when the plunger moves toward the distal end, thereby causing the drug to flow through the flexible canal, through the needle and out of the tip of the needle; a power supply positioned within the housing, the power supply providing power to the controller and the actuator; and a sensor positioned within the housing, the sensor configured to take measurements of rotations of the actuator and transmit the measurements to the controller to determine an amount of translation of the plunger, the controller notifying the subject of a malfunction if the actuator one of fails to rotate and rotates too slowly upon application of power.