发明名称 MODULATORS OF THE RELAXIN RECEPTOR 1
摘要 Disclosed are modulators of the human relaxin receptor 1, for example, of formula (I), wherein A, R1, and R2 are as defined herein, that are useful in treating mammalian relaxin receptor 1 mediated facets of human health, e.g., cardiovascular disease. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the disclosure, and a method for therapeutic intervention in a facet of mammalian health that is mediated by a human relaxin receptor 1.
申请公布号 US2015119426(A1) 申请公布日期 2015.04.30
申请号 US201314398830 申请日期 2013.03.15
申请人 The United States of America, as Represented by the Secretary, Dept. of Health & Human Services ;The Florida International University Board of Trustees 发明人 Marugan Juan Jose;Xiao Jingbo;Ferrer-Alegre Marc;Chen Catherine;Southall Noel;Zheng Wei;Agoulnik Alexander;Agoulnik Irina
分类号 C07C237/42;C07D213/81;C07D333/38;C07D213/82;C07C323/42;C07C317/40 主分类号 C07C237/42
代理机构 代理人
主权项
地址 Bethesda MD US