发明名称 |
IMPLANTABLE NEUROSTIMULATOR FOR PROVIDING ELECTRICAL STIMULATION OF CERVICAL VAGUS NERVES FOR TREATMENT OF CHRONIC CARDIAC DYSFUNCTION WITH BOUNDED TITRATION |
摘要 |
A system for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration is provided. The system includes a patient-operable external controller to transmit a plurality of unique signals. The system further includes an implantable neurostimulator, which includes a pulse generator to deliver electrical therapeutic stimulation tuned to restore autonomic balance through continuously-cycling, intermittent and periodic electrical pulses that result in creation and propagation (in both afferent and efferent directions) of action potentials within the cervical vagus nerve of a patient through a pair of helical electrodes via an electrically coupled nerve stimulation therapy lead. The neurostimulator also includes a recordable memory storing an autotitration operating mode that includes a maximum stimulation intensity and is configured to increase an intensity of the delivered electrical therapeutic stimulation up to a level not exceeding the maximum stimulation intensity upon receipt of one of the unique signals. |
申请公布号 |
US2015119959(A1) |
申请公布日期 |
2015.04.30 |
申请号 |
US201514591349 |
申请日期 |
2015.01.07 |
申请人 |
CYBERONICS, INC. |
发明人 |
Libbus Imad;Amurthur Badri;KenKnight Bruce H. |
分类号 |
A61N1/36;A61N1/372 |
主分类号 |
A61N1/36 |
代理机构 |
|
代理人 |
|
主权项 |
1. A vagus nerve neurostimulator for treatment of chronic cardiac dysfunction, comprising:
a pulse generator, wherein the pulse generator generates a pulsed electrical signal comprising:
a signal ON time;a signal OFF time;an output current;a signal frequency;a pulse width; anda duty cycle defined by dividing the signal ON time by the sum of the signal ON time and signal OFF time; a therapy lead; an electrode communicatively coupled to the pulse generator via the therapy lead; and a recordable memory storing a maximum stimulation intensity and an autotitration operating mode configured to cause the pulse generator to increase an intensity of the pulsed electrical signal up to a level not exceeding the maximum stimulation intensity. |
地址 |
Houston TX US |