发明名称 |
COMPOUNDS FOR USE IN PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES AND PAIN |
摘要 |
Compounds for use in prevention and treatment of neurodegenerative disease and pain are disclosed. In one embodiment of the invention, the compound is selected from the group consisting of N 6 -[(3-halothien-2-yl)methyl]adenosine, N 6 -[(4-halothien-2-yl)methyl]adenosine, and N 6 -[(5-halothien-2-yl)methyl]adenosine. In another embodiment of the invention, the compound is selected from the group consisting of N 6 -[(2-bromothien-3-yl)methyl]adenosine, N 6 -[(4-bromothien-3-yl)methyl]adenosine, N 6 -[(5-bromothien-3-yl)methyl]adenosine N 6 -[(2-chlorothien-3-yl)methyl]adenosine, N 6 -[(4-chlorothien-3-yl)methyl]adenosine, and N 6 -[(5-chlorothien-3-yl)methyl]adenosine. Also disclosed are methods of making and using the same. |
申请公布号 |
WO2015061426(A1) |
申请公布日期 |
2015.04.30 |
申请号 |
WO2014US61734 |
申请日期 |
2014.10.22 |
申请人 |
ACADEMIA SINICA;LIANG, CHI-MING |
发明人 |
FANG, JIM-MIN;LIN, YUN-LIAN;LIN, JUNG-HSIN;LIN, CHUN-JUNG;CHERN, YIJUANG;HUANG, NAI-KUEI;WANG, HUNG-LI;TU, BENJAMIN PANG-HSIEN;CHEN, CHIH-CHENG |
分类号 |
C07D498/02;C07D515/02 |
主分类号 |
C07D498/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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