| 发明名称 |
ANTI-PODOCALYXIN ANTIBODIES AND METHODS OF USING THE SAME |
| 摘要 |
The present invention is directed to compositions of matter useful for the treatment of cancer in mammals and to methods of using those compositions of matter for the same. Antibodies specific for podocalyxin designated Ab1 and 3G2 are disclosed, as is the use of said antibodies for the inhibition of growth of a tumor that expresses podocalyxin, and the use of said antibodies for targeting tumour endothelial cells that express podocalyxin. |
| 申请公布号 |
CA2928043(A1) |
申请公布日期 |
2015.04.30 |
| 申请号 |
CA20142928043 |
申请日期 |
2014.10.21 |
| 申请人 |
THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT;UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
BABCOOK, JOHN STEPHEN;HEDBERG, BRADLEY JOHN;HUGHES, MICHAEL R.;MCNAGNY, KELLY MARSHALL;ROSKELLEY, CALVIN D.;SNYDER, KIMBERLY ASHELY |
| 分类号 |
C07K16/30;A61K39/395;A61P35/00;C07K16/28;C12N15/13 |
主分类号 |
C07K16/30 |
| 代理机构 |
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