发明名称 BLOOD PLASMA BIOMARKERS FOR BEVACIZUMAB COMBINATION THERAPIES FOR TREATMENT OF BREAST CANCER
摘要 The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer, by adding bevacizumab (Avastin ®) to a chemotherapy regimen by determining the expression level, in particular the blood plasma expression level, of E-selectin, ICAM-1 or VEGFR-3 relative to control levels of patients diagnosed with HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer.
申请公布号 EP2864788(A1) 申请公布日期 2015.04.29
申请号 EP20130730890 申请日期 2013.06.24
申请人 F.HOFFMANN-LA ROCHE AG 发明人 KLAUSE, URSULA;MOORE, NICOLA;PALLAUD, CÉLINE;SCHERER, STEFAN;WILD, NORBERT
分类号 G01N33/574;A61K35/00 主分类号 G01N33/574
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