发明名称 MODULATION OF UBE3A-ATS EXPRESSION
摘要 Certain embodiments are directed to methods and compounds for inhibiting UBE3A-ATS, the endogenous antisense transcript of ubiquitin protein ligase E3A (UBE3A). Such methods and compounds are useful for inducing expression of paternal UBE3A in cells and animals.
申请公布号 EP2864479(A2) 申请公布日期 2015.04.29
申请号 EP20130809694 申请日期 2013.06.25
申请人 ISIS PHARMACEUTICALS, INC.;BAYLOR COLLEGE OF MEDICINE 发明人 RIGO, FRANK;WARD, AMANDA;BEAUDET, ARTHUR, L.;MENG, LINYAN
分类号 C12N15/113;A61K31/7088;C12N15/00 主分类号 C12N15/113
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