| 发明名称 |
1-[M-CARBOXAMIDO(HETERO)ARYL-METHYL]-HETEROCYCLYL-CARBOXAMIDE DERIVATIVES |
| 摘要 |
The present invention relates to 1-[m-carboxamido(hetero)aryl-methyl]-heterocycyl-carboxamide compounds of formula (I) wherein X, Ar1, R1, R2, R3, R4, R5a, R5b and p are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as CXCR7 receptor modulators. |
| 申请公布号 |
EP2864315(A2) |
申请公布日期 |
2015.04.29 |
| 申请号 |
EP20130759008 |
申请日期 |
2013.06.21 |
| 申请人 |
ACTELION PHARMACEUTICALS LTD. |
发明人 |
FRETZ, HEINZ;GUDE, MARKUS;GUERRY, PHILIPPE;KIMMERLIN, THIERRY;LEHEMBRE, FRANCOIS;PFEIFER, THOMAS;VALDENAIRE, ANJA |
| 分类号 |
C07D401/06;A61K31/445;A61K31/4523;A61K31/4545;A61P29/00;A61P35/00;A61P37/00;C07D211/62 |
主分类号 |
C07D401/06 |
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