发明名称 PRODRUGS OF D-GAMMA-GLUTAMYL-D-TRYPTOPHAN AND D-GAMMA-GLUTAMYL-L-TRYPTOPHAN
摘要 The present invention provides pro-drugs of D-gamma-glutamyl-[D/L]-tryptophan, said pro-drugs are compounds of Formula I or pharmaceutically acceptable salts thereof, wherein G is C1-C8 alkyl or benzyl, T is C1-C8 alkyl or benzyl, and * is a chiral carbon in a (R) or (S) configuration, provided that when * is in the (R) configuration, at least one of G and T is C5-C8 alkyl; and use of compounds of Formula I in a pharmaceutical composition.
申请公布号 ZA201307230(B) 申请公布日期 2015.04.29
申请号 ZA20130007230 申请日期 2013.09.26
申请人 APOTEX TECHNOLOGIES INC. 发明人 TAM TIM FAT;WANG YINGSHENG;XIN TAO;WODZINSKA JOLANTA MARIA;LEUNG-TOUNG REGIS;ZHAO YANQING;LI WANREN;RABADIA VRAJILAL S;SHAH BIRENKUMAR;FEENEY CHRISTOPHER JOHN
分类号 A61K;C07D;C07K 主分类号 A61K
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