发明名称 Camsylate salt of (1r,1'R,4R)- 4-methoxy-5-methyl-6'-[5-(prop-1-yn-1-yl)pyridin- 3-yl]-3'H-dispiro[cyclohexane-1,2'-inden-1'2'-imidazole]-4-amine and crystalline forms thereof for the treatment of A[beta]-related pathologies such as e.g. Alzheimer's disease
摘要 A camsylate salt of (1r,1'R,4R)-4-methoxy-5''-methyl-6'-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3'H-dispiro[cyclohexane-1,2'-inden-1'2'-imidazole]-4''-amine, pharmaceutical compositions containing the salt and therapeutic uses of the salt for treating Abeta-related pathologies such as Alzheimer's Disease, Down's syndrome, beta-amyloid angiopathy and conditions such as dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.
申请公布号 EP2864316(A1) 申请公布日期 2015.04.29
申请号 EP20130733415 申请日期 2013.06.20
申请人 ASTRAZENECA AB 发明人 BOHLIN, MARTIN, HANS;STEWART, CRAIG ROBERT
分类号 C07D401/10;A61K31/4439;A61P25/28 主分类号 C07D401/10
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