发明名称 |
Camsylate salt of (1r,1'R,4R)- 4-methoxy-5-methyl-6'-[5-(prop-1-yn-1-yl)pyridin- 3-yl]-3'H-dispiro[cyclohexane-1,2'-inden-1'2'-imidazole]-4-amine and crystalline forms thereof for the treatment of A[beta]-related pathologies such as e.g. Alzheimer's disease |
摘要 |
A camsylate salt of (1r,1'R,4R)-4-methoxy-5''-methyl-6'-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3'H-dispiro[cyclohexane-1,2'-inden-1'2'-imidazole]-4''-amine, pharmaceutical compositions containing the salt and therapeutic uses of the salt for treating Abeta-related pathologies such as Alzheimer's Disease, Down's syndrome, beta-amyloid angiopathy and conditions such as dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration. |
申请公布号 |
EP2864316(A1) |
申请公布日期 |
2015.04.29 |
申请号 |
EP20130733415 |
申请日期 |
2013.06.20 |
申请人 |
ASTRAZENECA AB |
发明人 |
BOHLIN, MARTIN, HANS;STEWART, CRAIG ROBERT |
分类号 |
C07D401/10;A61K31/4439;A61P25/28 |
主分类号 |
C07D401/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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