摘要 |
The present invention provides a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, A1, A2, A3, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon. |
申请人 |
PFIZER INC. |
发明人 |
DIDIUK,MARY;FILIPSKI,KEVIN,J.;GUZMAN-PEREZ,ANGEL;LEE,ESTHER,C.;PFEFFERKORN,JEFFREY,A.;STEVENS,BENJAMIN;TU,MEIHUA |