| 发明名称 |
GUANINE ANALOGS AS TELOMERASE SUBSTRATES AND TELOMERE LENGTH AFFECTORS |
| 摘要 |
This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are incorporated into telomeres by telomerase thereby inhibiting elongation of telomeres. The compounds are useful in treating cancer and other cell proliferative diseases. |
| 申请公布号 |
EP2794624(A4) |
申请公布日期 |
2015.04.29 |
| 申请号 |
EP20120859248 |
申请日期 |
2012.12.21 |
| 申请人 |
GERON CORPORATION |
发明人 |
GRYAZNOV, SERGEI, M.;PRUZAN, RONALD, A.;PONGRACZ, KRISZTINA |
| 分类号 |
C07F9/6561;A61K31/675;A61K31/683;A61K31/685;A61K31/688;A61P35/00;A61P35/02;A61P35/04 |
主分类号 |
C07F9/6561 |
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