发明名称 Process for the preparation of Deferasirox
摘要 The present invention provides improved process for the preparation of Deferasirox of formula (I).
申请公布号 US9018389(B2) 申请公布日期 2015.04.28
申请号 US201113988361 申请日期 2011.11.04
申请人 Alembic Pharmaceuticals, Ltd. 发明人 Raman Jayaraman Venkat;Shah Hiral
分类号 C07D249/08 主分类号 C07D249/08
代理机构 McAndrews Held & Malloy, Ltd. 代理人 McAndrews Held & Malloy, Ltd.
主权项 1. A method for preparing Deferasirox comprising the step of: treating 2-(2-hydroxyphenyl)benz[e][1,3]oxazin-4-one with 4-hydrazinobenzoic acid in the presence of potassium hydrogen sulfate, sodium hydrogen sulfate, or a mixture thereof, a suitable solvent, and optionally in the presence of water.
地址 Gujarat, Vadodara IN