发明名称 |
Process for the preparation of Deferasirox |
摘要 |
The present invention provides improved process for the preparation of Deferasirox of formula (I). |
申请公布号 |
US9018389(B2) |
申请公布日期 |
2015.04.28 |
申请号 |
US201113988361 |
申请日期 |
2011.11.04 |
申请人 |
Alembic Pharmaceuticals, Ltd. |
发明人 |
Raman Jayaraman Venkat;Shah Hiral |
分类号 |
C07D249/08 |
主分类号 |
C07D249/08 |
代理机构 |
McAndrews Held & Malloy, Ltd. |
代理人 |
McAndrews Held & Malloy, Ltd. |
主权项 |
1. A method for preparing Deferasirox comprising the step of: treating 2-(2-hydroxyphenyl)benz[e][1,3]oxazin-4-one with 4-hydrazinobenzoic acid in the presence of potassium hydrogen sulfate, sodium hydrogen sulfate, or a mixture thereof, a suitable solvent, and optionally in the presence of water. |
地址 |
Gujarat, Vadodara IN |