| 发明名称 | DC-STAMP antibodies | ||
| 摘要 | Provided herein are antibodies that specifically bind an epitope of DC-STAMP. Specifically, provided herein are monoclonal antibodies that bind an epitope of DC-STAMP, wherein the epitope comprises the amino acid sequence Glu-Val-His-Leu-Lys-Leu-His-Gly-Glu-Lys-Gln-Gly-Thr-Gln (SEQ ID NO:1). Optionally, the epitope comprises the amino acid sequence His-Gly-Glu-Lys-Gln-Gly-Thr-Gln (SEQ ID NO:2). Optionally, the epitope comprises the amino acid sequence Lys-Gln-Gly-Thr-Gln (SEQ ID NO:3). | ||
| 申请公布号 | US9018358(B2) | 申请公布日期 | 2015.04.28 |
| 申请号 | US201013266629 | 申请日期 | 2010.04.29 |
| 申请人 | University of Rochester | 发明人 | Schwarz Edward M.;Mensah Kofi A.;Chiu Yahui Grace;Ritchlin Christopher T. |
| 分类号 | C07K16/00;C12P21/08;C07K16/28;C07K14/705 | 主分类号 | C07K16/00 |
| 代理机构 | Kilpatrick Townsend & Stockton, LLP | 代理人 | Kilpatrick Townsend & Stockton, LLP |
| 主权项 | 1. A monoclonal antibody that specifically binds to an epitope of DC-STAMP, wherein the epitope comprises the amino acid sequence Glu-Val-His-Leu-Lys-Leu-His-Gly-Glu-Lys-Gln-Gly-Thr-Gln (SEQ ID NO:1). | ||
| 地址 | Rochester NY US | ||