Esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them, and their use as inhibitors of the thioredoxin—thioredoxin reductase system

摘要

The subject of the present invention are novel esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them and their use in the production of drugs for the prophylaxis or treatment of oncogenic diseases and diseases connected with increased cell proliferation.

主权项

1. A compound with the general formula (I): . . . R3 is a trifluoromethyl or 2,6-di(trifluoromethyl)benzoyl or a benzoyl having at positions 2,6 two identical or different halide substituents selected from the group consisting of CI, Br, I or a pharmaceutically acceptable salt thereof.