| 发明名称 | Adenovirus vectors | ||
| 摘要 | An adenoviral vector comprising a promoter further comprising a fragment of the 5′ untranslated region of the CMV IE1 gene including intron A and a nucleic acid sequence encoding a pathogen or tumor antigen for use as a medicament. | ||
| 申请公布号 | US9017696(B2) | 申请公布日期 | 2015.04.28 |
| 申请号 | US200812595574 | 申请日期 | 2008.04.10 |
| 申请人 | Isis Innovation Limited | 发明人 | Draper Simon;Reyes Arturo;Sridhar Saranya;Hill Adrian;Gilbert Sarah;Goodman Anna |
| 分类号 | A61K39/23;A61K39/015;A61K39/04;A61K48/00;C07K16/20;C07K14/78;C12N15/86 | 主分类号 | A61K39/23 |
| 代理机构 | Dann, Dorfman, Herrell & Skillman | 代理人 | Rigaut Kathleen D.;Netter, Jr. Robert C.;Dann, Dorfman, Herrell & Skillman |
| 主权项 | 1. A recombinant adenoviral vector comprising a promoter and at least one nucleic acid sequence encoding an antigen of a bacterial pathogen or a parasitic pathogen under the control of said promoter, wherein said promoter consists of SEQ ID NO: 7 and wherein said parasitic antigen is not a murine malaria parasite antigen. | ||
| 地址 | Oxford GB | ||