| 发明名称 | Bonding products of aminated polysaccharides | ||
| 摘要 | The invention relates to a bonding product comprising at least the polysaccharides T1 and T2, characterized in that a) the monosaccharides from which the polysaccharides T1 and T2 are constructed are partially or completely bonded to each other alpha-1,4-glycosidically and b) at least one of the polysaccharides T1 and/or T2 comprises at least one amino group and c) T1 and T2 are chemically bonded to each other covalently by at least one linker Z and d) T1 and/or T2 carries m groups -(L-A), wherein A is an active pharmaceutical ingredient and/or a fluorescence label, L is a second linker, by which T1 and/or T2 is covalently bonded to A, and m is an integer, which is 0 or at least 1. | ||
| 申请公布号 | US9018372(B2) | 申请公布日期 | 2015.04.28 |
| 申请号 | US201013256018 | 申请日期 | 2010.03.31 |
| 申请人 | B. Braun Melsungen AG | 发明人 | Meier Bernd Horst;Jankowiak-Meier Iris;Meier Nele;Meier Clara |
| 分类号 | C07H1/00;C08B37/08;C08B37/10;A61K31/726;A61K31/722;A61K31/736;A61K31/718;A61K31/715;A61K47/48;A61K49/00 | 主分类号 | C07H1/00 |
| 代理机构 | Dority & Manning, P.A. | 代理人 | Dority & Manning, P.A. |
| 主权项 | 1. A bonding product comprising polysaccharides T1 and T2, characterized in that a) the monosaccharides from which the polysaccharides T1 and T2 are constituted are completely linked together via alpha-1,4-glycosidic linkages, and b) at least one of polysaccharides T1 and T2 has at least one amino group, and c) T1 and T2 are bonded together chemically by covalent bonds through at least one linker Z; and d) at least one of T1 and T2 bears m groups -(L-A), wherein A is a medicinally active substance selected from the group consisting of glucosaminoglycans and glucosaminoglycan derivatives;L is a second linker through which at least one of T1 and T2 is covalently bonded with A, andm is an integer of at least 1. | ||
| 地址 | Melsungen DE | ||