Knowledge-based automatic image segmentation

摘要

A method for medical image segmentation includes accessing and updating a knowledge-base. First, a medical image is received and a sparse landmark signature is computed based on the medical image. Next, either a representative or a cohort average reference image set is selected. A portion of either representative reference image set or the cohort average reference image set is deformed to generate mappings to the medical image set. A segmentation for each structure of interest of the medical image set is determined. The knowledge-base is searched for representative matches to form a plurality of sub-volume base sets comprising a plurality of reference image set sub-volumes. A portion of the plurality of reference image set sub-volumes of the plurality of sub-volume base sets is deformed to generate mappings from the plurality of sub-volume base sets to corresponding structures of interest of the medical image set. A weighted-average segmentation for the plurality of structures of interest in the medical image set is calculated.

主权项

1. A method for segmenting an image data set, the method comprising:
accessing a medical image set; accessing a plurality of representative reference image sets from a knowledge-base, wherein each of the representative reference image sets comprises an image set of a corresponding single subject; averaging the plurality of representative reference image sets to produce an average reference image set, wherein the average reference image set is a statistical average of reference image sets within the knowledge-base, wherein the statistical average of the reference image sets within the knowledge-base is determined by determining a statistical average of a quantity of deformablv or affinelv registered reference image sets within the knowledge-base; deforming at least a portion of the average reference image set to the medical image set; and determining a segmentation for a plurality of structures of interest in the medical image set based upon information in the average reference image set.