发明名称 |
Treatment of cancer using benzoic acid derivatives |
摘要 |
The present invention provides a method of treating cancer using benzoic acid derivatives, alone or in combination with standard treatments such as chemotherapy and radiotherapy. Also provided are methods of screening for benzoic derivatives based on their ability to inhibit the enzyme tyrosinase or to bind to and activate PXR/SXR xenobiotic receptors. |
申请公布号 |
US9018259(B2) |
申请公布日期 |
2015.04.28 |
申请号 |
US201213470819 |
申请日期 |
2012.05.14 |
申请人 |
New York University |
发明人 |
Brooks Peter C.;Morais Danielle;Liebes Leonard;Rodriguez Dorothy |
分类号 |
A61K31/196;A61K31/337;A61K31/192 |
主分类号 |
A61K31/196 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A pharmaceutical composition comprising:
(a) a therapeutic amount of a compound having the formula: (b) at least one pharmaceutically acceptable carrier, and (c) a chemotherapeutic compound. |
地址 |
New York NY US |