| 发明名称 | Apoptotically active peptides | ||
| 摘要 | Specific amino acid sequences and peptides and/or peptide mimetics deducted therefrom influencing apoptosis, and the use thereof for the production of pharmaceuticals as diagnostic tools are shown. | ||
| 申请公布号 | US9017693(B2) | 申请公布日期 | 2015.04.28 |
| 申请号 | US201012977672 | 申请日期 | 2010.12.23 |
| 申请人 | Cytotools AG | 发明人 | Freyberg Mark A.;Friedl Peter;Kaiser Dirk |
| 分类号 | A61K38/00;A61K38/04;C07K14/47 | 主分类号 | A61K38/00 |
| 代理机构 | Marshall, Gerstein & Borun LLP | 代理人 | Marshall, Gerstein & Borun LLP |
| 主权项 | 1. Apoptotically active substance comprising a peptide having one of the amino acid sequences selected from the group consisting of M-V-V-Y-F-R (SEQ ID NO: 12), R-A-Y-V-V-A (SEQ ID NO: 13), R-L-Y-V-V-M (SEQ ID NO: 14), R-P-Y-V-V-M (SEQ ID NO: 15), R-S-Y-V-V-M (SEQ ID NO: 16), R-C-Y-V-V-M (SEQ ID NO: 17), m-v-v-y-f-r (D-amino acids) (SEQ ID NO: 18) and m-v-v-y-a-r (D-amino acids) (SEQ ID NO: 19), wherein the peptide induces apoptosis wherein the apoptotically active peptide has less than 15 amino acids. | ||
| 地址 | Darmstadt DE | ||