发明名称 Phoenixin peptides
摘要 Human phoenixin peptides, analogs and mimetics useful in production of anti-phoenixin antibodies, diagnostic screening and assays, and in modulating cellular concentration of cAMP, and treatment of disorders related to cAMP or Ca2+ concentration in cells, modulating hypertension and cardiovascular function, modulating gonadotrophs and gastric emptying.
申请公布号 US9018350(B2) 申请公布日期 2015.04.28
申请号 US201214119866 申请日期 2012.05.25
申请人 Phoenix Pharmaceuticals, Inc. 发明人 Chang Jaw-Kang;Lyu Rong-Ming
分类号 C07K7/08;C07K14/575;C07K14/705;A61K38/00 主分类号 C07K7/08
代理机构 CR Miles, P.C. 代理人 Miles Craig R.;CR Miles, P.C.
主权项 1. A purified and isolated polypeptide consisting of the amino acid sequence selected from the group consisting of SEQ ID NOS: 2 through 60, wherein said purified and isolated polypeptide includes one or more of the following modifications: a substitution of an L form amino acid residue with a D form amino acid residue, an amide C-terminus, and an acetyl N-terminus.
地址 Burlingame CA US