发明名称 |
Phoenixin peptides |
摘要 |
Human phoenixin peptides, analogs and mimetics useful in production of anti-phoenixin antibodies, diagnostic screening and assays, and in modulating cellular concentration of cAMP, and treatment of disorders related to cAMP or Ca2+ concentration in cells, modulating hypertension and cardiovascular function, modulating gonadotrophs and gastric emptying. |
申请公布号 |
US9018350(B2) |
申请公布日期 |
2015.04.28 |
申请号 |
US201214119866 |
申请日期 |
2012.05.25 |
申请人 |
Phoenix Pharmaceuticals, Inc. |
发明人 |
Chang Jaw-Kang;Lyu Rong-Ming |
分类号 |
C07K7/08;C07K14/575;C07K14/705;A61K38/00 |
主分类号 |
C07K7/08 |
代理机构 |
CR Miles, P.C. |
代理人 |
Miles Craig R.;CR Miles, P.C. |
主权项 |
1. A purified and isolated polypeptide consisting of the amino acid sequence selected from the group consisting of SEQ ID NOS: 2 through 60, wherein said purified and isolated polypeptide includes one or more of the following modifications: a substitution of an L form amino acid residue with a D form amino acid residue, an amide C-terminus, and an acetyl N-terminus. |
地址 |
Burlingame CA US |