Preparation for vaccination, vaccination method and use of a vaccination preparation

摘要

The present invention relates to a pharmaceutical preparation, comprising at least one Toll-like receptor ligand and at least one peptide. The invention also relates to the use of such a pharmaceutical preparation and to a vaccination method.

主权项

1. A pharmaceutical preparation which comprises from 0.1% to 10% by weight of (a) at least one Toll-like receptor ligand selected from TLR7 ligands, from 0.01% to 30% by weight of (b) at least one peptide selected from (i) major histocompatibility complex class I ligands, (ii) major histocompatibility complex class II ligands, and (iii) peptides which comprise one or more of these histocompatibility complex ligands and are capable of being presented by at least one of a MHC class I molecule and a MHC class II molecule, and from 0.1% to 99.9% by weight of (c) one or more substances selected from carriers, adjuvants and additives, in each case based on a total weight of the preparation; wherein said pharmaceutical preparation elicits increased T cell mediated immune response compared to peptide (b) alone.