| 发明名称 | Nicotinic acetylcholine receptor agonists | ||
| 摘要 | The invention provides novel nicotinic acetylcholine receptor agonists, for example, phantasmidine and derivatives thereof, for example a compound of formula (I). Also disclosed are methods of treating disorders responsive to nicotinic acetylcholine receptor agonists such as Alzheimer's disease, schizophrenia, Myasthenia Gravis, Tourette's syndrome, Parkinson's disease, epilepsy, pain, and cognitive dysfunction by treatment with the nicotinic acetylcholine for agonists.; | ||
| 申请公布号 | US9018227(B2) | 申请公布日期 | 2015.04.28 |
| 申请号 | US201113583420 | 申请日期 | 2011.03.18 |
| 申请人 | Indiana State University;The United States of America, as Represented by the Secretary, Department of Health and Human Services | 发明人 | Fitch Richard W.;Spande Thomas F.;Garraffo H. Martin;Yeh Herman J. C.;Daly John W. |
| 分类号 | A01N43/42;A61K31/44;C07D471/00;C07D491/00;C07D498/00;C07D513/00;C07D515/00;A61K31/437;C07D491/14;A01N43/90;C07D491/147;G01N33/50 | 主分类号 | A01N43/42 |
| 代理机构 | Leydig, Voit & Mayer, Ltd. | 代理人 | Leydig, Voit & Mayer, Ltd. |
| 主权项 | 1. A compound of the formula: wherein R is CH3 or CH3CO, or a pharmaceutically acceptable salt thereof. | ||
| 地址 | Terre Haute IN US | ||