| 发明名称 | Peptides for suppressing inflammation | ||
| 摘要 | Provided herein are peptides that exhibit ApoE biological activity, as well as compositions and pharmaceutical formulations that include the peptides. The peptides, compositions, and methods disclosed herein have broad applications as they can be used to treat a broad spectrum of injury, diseases, disorders, and clinical indications. | ||
| 申请公布号 | US9018169(B2) | 申请公布日期 | 2015.04.28 |
| 申请号 | US201213981238 | 申请日期 | 2012.03.16 |
| 申请人 | Duke University | 发明人 | Laskowitz Daniel T.;Dawson Hana;Kolls Brad |
| 分类号 | A61K38/00;C07K7/06;C07K14/775 | 主分类号 | A61K38/00 |
| 代理机构 | Myers Bigel Sibley & Sajovec, P.A. | 代理人 | Myers Bigel Sibley & Sajovec, P.A. |
| 主权项 | 1. An isolated pentapeptide of Formula I:(SEQ ID NO: 1)X1-X2-X3-X4-X5 or a salt thereof, wherein X1 is V; X2 is S; X3 is K or R; X4 is K or R; and X5 is R; and wherein said pentapeptide is optionally N-terminal acetylated and/or C-terminal amidated. | ||
| 地址 | Durham NC US | ||