摘要 |
<p>The present invention relates to a recombinant vector for screening anticancer agents including a human Noxin promoter fragment and a screening method of anticancer agents using the same wherein a vector is made having a human Noxin promoter combination and luciferase which is a reporter, and is transformed in a cancer cell line and treated with a novel drug, thereby enabling the vector including a transcription factor having a binding part to have a decreased NFAT2 function due to the drug in expressed transgenic cancer cell lines and decreasing the transcription activity and the expression of human Noxin and inhibiting cell growth, which enables the recombinant vector for screening the anticancer agent including the human Noxin promoter fragment to be used for screening anticancer materials.</p> |