发明名称 |
Fe(iii) complexes for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anaemias |
摘要 |
Disclosed are Fe(III) complexes with bidentate pyrimidine ligands (formula I) and pharmaceutical compositions for use in the treatment and prevention of iron dificency and anaema. In comparison to classical preparations of Fe(II) salts, the complexes have fewer side effects, lower toxicity, low molecular weight, high complex stability and do not lead to free Fe which catalyses the formation of reactive oxygen species that cause oxidative stress. |
申请公布号 |
NZ616045(A) |
申请公布日期 |
2015.04.24 |
申请号 |
NZ20120616045 |
申请日期 |
2012.03.28 |
申请人 |
VIFOR (INTERNATIONAL) AG |
发明人 |
BARK THOMAS;BUHR WILM;BURCKHARDT SUSANNA;BURGERT MICHAEL;CANCLINI CAMILLO;DÜRRENBERGER FRANZ;FUNK FELIX;GEISSER PETER OTTO;KALOGERAKIS ARIS;MAYER SIMONA;PHILIPP ERIK;REIM STEFAN;SIEBER DIANA;SCHMITT JÖRG;SCHWARZ KATRIN |
分类号 |
C07D239/34;A61K31/26;A61P7/00;C07D239/30;C07D239/80;C07F15/02 |
主分类号 |
C07D239/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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