发明名称 Triazolopyridine compounds as pde10a inhibitors
摘要 <p>Provided are triazolopyridine derivative compounds of the general formula (I), wherein the variables are as defined in the specification. Examples of the compounds include 2-Methyl-4-(pyrrolidine-1-carbonyl)-2H-pyrazole-3-carboxylic acid (2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-amide and 2-Methyl-4-(pyrrolidine-1-carbonyl)-2H-pyrazole-3-carboxylic acid [2-(3-methoxypyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-amide. The compounds are phosphodiesterase 10A (PDE10A) inhibitors. The compounds may be useful in the treatment of cancer and neurological disorders.</p>
申请公布号 NZ621597(A) 申请公布日期 2015.04.24
申请号 NZ20120621597 申请日期 2012.09.17
申请人 F. HOFFMANN-LA ROCHE AG 发明人 FLOHR ALEXANDER;GROEBKE ZBINDEN KATRIN;KOERNER MATTHIAS
分类号 C07D471/04;A61K31/437;A61P25/00;A61P35/00 主分类号 C07D471/04
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