| 发明名称 |
HETEROARYL LINKED QUINOLINYL MODULATORS OF ROR.GAMMA.T |
| 摘要 |
The present invention comprises compounds of Formula I wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification, The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1. |
| 申请公布号 |
CA2926443(A1) |
申请公布日期 |
2015.04.23 |
| 申请号 |
CA20132926443 |
申请日期 |
2013.10.15 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
LEONARD, KRISTI A.;BARBAY, KENT;EDWARDS, JAMES P.;KREUTTER, KEVIN D.;KUMMER, DAVID A.;MAHAROOF, UMAR;NISHIMURA, RACHEL;URBANSKI, MAUD;VENKATESAN, HARIHARAN;WANG, AIHUA;WOLIN, RONALD L.;WOODS, CRAIG R.;FOURIE, ANNE;XUE, XIAOHUA;CUMMINGS, MAXWELL D. |
| 分类号 |
C07D215/00 |
主分类号 |
C07D215/00 |
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