发明名称 ALKYL LINKED QUINOLINYL MODULATORS OF RORyt
摘要 The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
申请公布号 WO2015057629(A1) 申请公布日期 2015.04.23
申请号 WO2014US60375 申请日期 2014.10.14
申请人 JANSSEN PHARMACEUTICA NV;LEONARD, KRISTI A. 发明人 LEONARD, KRISTI A.;BARBAY, KENT;EDWARDS, JAMES P.;KREUTTER, KEVIN D.;KUMMER, DAVID A.;MAHAROOF, UMAR;NISHIMURA, RACHEL;URBANSKI, MAUD;VENKATESAN, HARIHARAN;WANG, AIHUA;WOLIN, RONALD L.;WOODS, CRAIG R.;FOURIE, ANNE;XUE, XIAOHUA;CUMMINGS, MAXWELL D.
分类号 A01N43/54;A01N43/42;C07D239/72;C07D453/04 主分类号 A01N43/54
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