发明名称 NEW PHENYL-DIHYDROPYRIDINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS
摘要 The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R 4, R 5, R 6, R7, R 8, R 9, R10, R11, R12, A1 and n are as described herein, compositions including the compounds and methods of using the compounds in the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrom.
申请公布号 WO2015055604(A1) 申请公布日期 2015.04.23
申请号 WO2014EP71943 申请日期 2014.10.14
申请人 F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. 发明人 AEBI, JOHANNES;AMREIN, KURT;BRITTON, ROBERT;HORNSPERGER, BENOIT;KUHN, BERND;MAERKI, HANS P.;MARTIN, RAINER E.;MAYWEG, ALEXANDER V.;TAN, XUEFEI
分类号 C07D221/04;A61K31/435;A61P5/40;A61P9/04;A61P9/12;A61P13/12 主分类号 C07D221/04
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