摘要 |
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R 4, R 5, R 6, R7, R 8, R 9, R10, R11, R12, A1 and n are as described herein, compositions including the compounds and methods of using the compounds in the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrom. |
申请人 |
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. |
发明人 |
AEBI, JOHANNES;AMREIN, KURT;BRITTON, ROBERT;HORNSPERGER, BENOIT;KUHN, BERND;MAERKI, HANS P.;MARTIN, RAINER E.;MAYWEG, ALEXANDER V.;TAN, XUEFEI |