发明名称 |
METHOD OF MICROWAVE VACUUM DRYING SPHERICAL-SHAPED PELLETS OF BIOLOGICAL MATERIALS |
摘要 |
Methods for preparing dried pellets of biological materials are described. The pellets can have a substantially spherical shape and are prepared by freezing droplets of a liquid composition of a desired biological material on a solid surface followed by microwave vacuum drying the frozen droplets. These methods are useful for preparing dried pellets having a high concentration of a desired biological material, in particular a therapeutic protein or vaccine, and which have a faster reconstitution time than lyophilized powder cakes prepared in vials. |
申请公布号 |
CA2927431(A1) |
申请公布日期 |
2015.04.23 |
申请号 |
CA20142927431 |
申请日期 |
2014.10.13 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
BHAMBHANI, AKHILESH;EVANS, ROBERT K.;SINACOLA, JESSICA;LIZZANO, REBECCA |
分类号 |
C07K1/36 |
主分类号 |
C07K1/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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