摘要 |
PROBLEM TO BE SOLVED: To provide novel compounds useful for the treatment of the infection and disease of Clostridium difficile-associated disease (CDAD).SOLUTION: The present invention provides compounds represented by formula (I), compositions comprising the compounds, and methods of treating bacterial disease and infection using the compounds, where L is a direct bond or a linker; Rand Rare H or C1-6 alkyl, aryl, heteroaryl or the like, with at least one of Rand Rbeing cyclic; Xand Xare N or CR; Xis NR, O or S; and Xis a NH group. |