| 发明名称 |
Transcription Factor Mediated Programming Towards Megakaryocytes |
| 摘要 |
This invention relates to the forward programming of pluripotent stem cells (PSCs) into megakaryocyte (MK) progenitor cells using the transcription factors GATA1, FLI1 and TAL1. Methods of producing megakaryocyte (MK) progenitor cells and subsequently differentiating them into mature megakaryocytes are provided. |
| 申请公布号 |
US2015111296(A1) |
申请公布日期 |
2015.04.23 |
| 申请号 |
US201314407044 |
申请日期 |
2013.06.19 |
| 申请人 |
Cambridge Enterprise Limited |
发明人 |
Pedersen Roger;Ouwehand Willem;Moreau Thomas;Ghevaert Cedric;Trotter Matthew |
| 分类号 |
C12N5/078 |
主分类号 |
C12N5/078 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
Cambridge GB |
