发明名称 |
TAIL VARIANT OF OXIDATION-REDUCTION ACTIVITY THERAPEUTIC AGENT FOR THERAPY OF MITOCHONDRIAL DISEASE AND RELATED CONDITION AND FOR ADJUSTMENT OF ENERGY BIOMARKER |
摘要 |
PROBLEM TO BE SOLVED: To provide a compound useful for therapy or suppression of diseases due to mitochondrial diseases and for adjustment of an energy biomarker in a subject.SOLUTION: A method of treating a mitochondrial disease, adjusting 1 or more energy biomarkers, normalizing 1 or more energy biomarkers, or enhancing 1 or more energy biomarkers comprises a step of administering a therapeutically effective amount of a hydroquinone compound represented by the formula or an oxidized form thereof (a quinone compound) to a subject (Rto Rare each independently a C1 to 4 alkyl or the like; and Ris a C1 to 20 alkyl, alkenyl or the like.) |
申请公布号 |
JP2015078224(A) |
申请公布日期 |
2015.04.23 |
申请号 |
JP20140254928 |
申请日期 |
2014.12.17 |
申请人 |
EDISON PHARMACEUTICALS INC |
发明人 |
MILLER GUY M;HECHT SIDNEY M |
分类号 |
A61K31/05;A61K31/122;A61P3/10;A61P9/00;A61P15/12;A61P21/02;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P27/02;A61P35/00;A61P43/00;C07C39/08;C07C50/02;C07C50/06 |
主分类号 |
A61K31/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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