| 发明名称 |
THERAPEUTIC STRATEGY FOR TREATING AUTOIMMUNE AND DEGENERATIVE DISEASES |
| 摘要 |
Numerous diseases have been linked to the production of effector cells. The present invention relates to the realization that effector cells are cycling in these diseases. In addition, the present invention relates to the determination that regulator cells are cycling in degenerative diseases. Based on these realizations, the present invention provides methods for treating conditions such as autoimmune diseases, degenerative diseases, and graft-versus-host disease. The present invention also relates to methods of determining when therapy should be administered to a patient. |
| 申请公布号 |
US2015110805(A1) |
申请公布日期 |
2015.04.23 |
| 申请号 |
US201414579487 |
申请日期 |
2014.12.22 |
| 申请人 |
ImmunAid Pty Ltd. |
发明人 |
Ashdown Martin Leonard;Ashdown Luisa Maria |
| 分类号 |
A61K39/00;C07K16/28;G01N33/68;C07D471/18;G01N33/564;G01N33/569;C12N15/113;C07D305/14 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for analysing effector cell and/or regulator cell cycling to determine when an agent should be administered to a patient suffering from a disease characterized by the production of effector cells, the method comprising monitoring the patient, or samples obtained therefrom, for fluctuations in at least one of: a) effector cell numbers and/or activity, b) regulator cell numbers and/or activity, c) a molecule associated with the disease, and/or d) an immune system marker. |
| 地址 |
Fitzroy AU |
