PHENYL-SUBSTITUTED COMPOUND, PHARMACEUTICAL COMPOSITION AND USES THEREOF

摘要

Disclosed are a phenyl-substituted compound with structures represented by formula (1) and formula (2), a pharmaceutical composition and uses thereof. The compound can remarkably show in vivo and in vitro that the compound can kill and/or inhibit multiple kinds of tumor cells of human beings and animals, can remarkably accelerate apoptosis and necrosis of the tumor cells, regulate growth cycles of the tumor cells, and inhibit proliferation of the tumor cells. In a same dosage, a cell toxic effect of the compound to normal cells of human bodies is remarkably lower than a cell toxic effect to tumor cells of human beings. The combined use of the compound and a clinical antitumor drug has a remarkable coordinated antitumor effect. The compound and a pharmaceutically acceptable salt thereof can be used for preparing antitumor drugs, antitumor pharmaceutical compositions, combined antitumor pharmaceutical compositions, or auxiliary antitumor health care products.