| 发明名称 |
ENZYME USED IN BIOSYNTHESIS OF 1, 4-BDO AND SCREENING METHOD OF THE SAME |
| 摘要 |
Recombinant butyraldehyde dehydrogenases (Blds) with improved production of 1,4-BDO, as well as recombinant microorganisms comprising polynucleotides encoding the recombinant Blds, and methods of producing 1,4-BDO by using the recombinant microorganisms. |
| 申请公布号 |
US2015111268(A1) |
申请公布日期 |
2015.04.23 |
| 申请号 |
US201414504279 |
申请日期 |
2014.10.01 |
| 申请人 |
SAMSUNG ELECTRONICS CO., LTD. ;AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION |
发明人 |
Park Jinhwan;Lee Pyungcheon;Park Jaechan;Lee Youngmin;Lee Wooyong;Park Jinwoo;Cho Kwangmyung;Hwang Heejin |
| 分类号 |
C12N9/02;C12P7/24 |
主分类号 |
C12N9/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A non-naturally occurring butyraldehyde dehydrogenase (bld) mutant polypeptide that catalyzes the conversion of 4-hydroxybutyryl-CoA into 4-hydroxybutyraldehyde, wherein the wild type bld comprises the amino acid sequence of SEQ ID NO: 1, wherein the bld mutant polypeptide comprises amino acid sequence of SEQ ID NO: 2, 3, 4, 5, 6, or 7. |
| 地址 |
SUWON-SI KR |
